99mTc-MAA–Based Dosimetry for Liver Cancer Treated Using 90Y-Loaded Microspheres: Known Proof of Effectiveness
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چکیده
منابع مشابه
Sze Microspheres : Known Proof of Effectiveness Y - Loaded 90 Based Dosimetry for Liver Cancer Treated Using −
1. Lam MGEH, Goris ML, Iagaru AH, Mittra ES, Louie JD, Sze DY. Prognostic utility of 90Y radioembolization dosimetry based on fusion 99mTc-macroaggregated albumin–99mTc-sulfur colloid SPECT. J Nucl Med. 2013;54:2055–2061. 2. Garin E, Lenoir L, Rolland Y, et al. 99mTc-MAA SPECT/CT based dosimetry accurately predicts tumour response and survival in HCC patients treated with 90Y-loaded glass micro...
متن کاملQuantitative comparison of yttrium-90 (90Y)-microspheres and technetium-99m (99mTc)-macroaggregated albumin SPECT images for planning 90Y therapy of liver cancer.
Yttrium-90 ((90)Y)-microspheres administered via the hepatic artery has been used for the treatment of unresectable primary or metastatic cancer in the liver. Prior to (90)Y therapy, however, the (90)Y administered activity and the percent shunting to lungs must be determined, most commonly by gamma camera imaging of technetium-99m ((99m)Tc)-macroaggregated albumin (MAA). The purpose of the cur...
متن کاملPrognostic utility of 90Y radioembolization dosimetry based on fusion 99mTc-macroaggregated albumin-99mTc-sulfur colloid SPECT.
UNLABELLED Planning hepatic (90)Y radioembolization activity requires balancing toxicity with efficacy. We developed a dual-tracer SPECT fusion imaging protocol that merges data on radioactivity distribution with physiologic liver mapping. METHODS Twenty-five patients with colorectal carcinoma and bilobar liver metastases received whole-liver radioembolization with resin microspheres prescrib...
متن کاملA Comparison of Techniques for 90Y PET/CT Image-Based Dosimetry Following Radioembolization with Resin Microspheres
(90)Y PET/CT following radioembolization has recently been established as a viable diagnostic tool, capable of producing images that are both quantitative and have superior image quality than alternative (90)Y imaging modalities. Because radioembolization is assumed to be a permanent implant, it is possible to convert quantitative (90)Y PET image sets into data representative of spatial committ...
متن کاملInternal pair production of 90Y permits hepatic localization of microspheres using routine PET: proof of concept.
UNLABELLED Radioembolization with 90Y microspheres represents a novel transarterial radiation treatment for liver tumors. The purpose of this pilot study was to evaluate the findings of postimplantation PET/CT of 90Y glass microspheres. METHODS Three patients with hepatocellular carcinoma and 2 patients with liver metastases (1 neuroendocrine, 1 colorectal) underwent PET/CT after radioemboliz...
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ژورنال
عنوان ژورنال: Journal of Nuclear Medicine
سال: 2014
ISSN: 0161-5505,2159-662X
DOI: 10.2967/jnumed.114.137422